Mark Buehrle has (for some unknown reason) some significant home/road splits this season. They're reverse of what you would expect from a pitcher who spends half his time pitching in USCF. He owns a 3-8 record away from USCF to go along with a 5.34 ERA and a .870 OPS allowed. Worse yet, the White Sox own a dismal 3-11 record in games Buehrle starts away from USCF this season.
I know next to nothing about opposing starter Alfredo Aceves, but UribeAuction has posted a brief scouting report. Looking at his minor league numbers combined with his scouting report, he seems like a cross between Nick Blackburn and Sox killer Shaun Marcum. Blackburn shut down the Sox in a couple of his early outings before they seemed to figure him out a bit.
Given the pitching matchup, the Sox dismal road record, and their two steps forward one step back cha-cha through the season, this one looks like your SSH lead pipe lock of the century. Don't bother watching. This one is over before it starts.