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1910
Comiskey Park hosted the first night game ever played in a major league ballpark, as two Chicago amateur clubs played before 3,500 fans. Nineteen arc lights were strung up along the perimeter of the field to accomplish the feat.
1911
Ed Walsh fired a no-hitter against the Red Sox at Comiskey Park. It was the first time a White Sox pitcher threw a no-hitter in that ballpark. The final was 5-0. Walsh only allowed one base runner, with a walk to Clyde Engle in the fourth inning.
2007
In the midst of a dismal season, the Sox produced one highlight: They cranked out four home runs in the seventh inning of a game at U.S. Cellular Field and beat the Devil Rays, 5-4. The home runs were hit by A.J. Pierzynski, Jermaine Dye, Juan Uribe and Josh Fields.